PUBLIC RESEARCH HUB
An open index of peer-reviewed molecular hydrogen research. Sourced from PubMed (NCBI/NIH), OpenAlex, and ClinicalTrials.gov. No paid placement, no editorial bias, no 'studies we like' — just the public record.
FEATURED · CURATED FOR CLARITY
A hand-picked set of the most-cited and most-instructive peer-reviewed papers in the field. Every citation has been verified against PubMed and is linked to its original source.
FEATURED STUDY · #1
The foundational paper. Showed that hydrogen gas selectively reduces the hydroxyl radical — the most cytotoxic reactive oxygen species — while leaving the signaling ROS the body uses intact. In a rat model, hydrogen inhalation markedly suppressed brain injury from oxidative stress.
FEATURED STUDY · #2
Phase 1 safety study. Eight healthy adults inhaled 2.4% hydrogen gas for up to 72 hours. No clinically significant adverse events and no changes in vital signs, pulmonary function, neurologic exam, or blood markers of organ injury.
FEATURED STUDY · #3
Narrative review covering 64 human studies and 81 registered clinical trials of molecular hydrogen therapy. Documents consistent safety signals across every delivery method studied — drinking hydrogen-rich water, inhaling hydrogen gas, and hydrogen-rich saline.
FEATURED STUDY · #4
Pilot RCT in 12 resistance-trained men. Hydrogen-rich water significantly reduced blood lactate 5 minutes post-exercise and reduced perceived muscle soreness 24 hours after intense squatting, compared with placebo.
FEATURED STUDY · #5
Randomized double-blind placebo-controlled crossover trial in elite female athletes completing two-a-day training. Hydrogen-rich water improved recovery markers between sessions compared with placebo.
FEATURED STUDY · #6
Randomized double-blind placebo-controlled crossover trial in 18 trained men. Eight days of hydrogen-rich water significantly increased total power output and repetitions during half-squat resistance training — but did not improve subjective soreness or jump performance. An honest mixed result, included for transparency.
FEATURED STUDY · #7
Systematic review and meta-analysis of RCTs in healthy adults. Hydrogen supplementation was associated with favorable changes in oxidative-stress biomarkers after exercise, with moderate heterogeneity across studies.
FEATURED STUDY · #8
8-week randomized double-blind placebo-controlled trial in 30 subjects with type 2 diabetes or impaired glucose tolerance. Hydrogen-rich water was associated with improved lipid profile (decreased modified LDL, increased HDL) and favorable glucose-metabolism changes.
ALL STUDIES · LIVE INDEX
Search, sort, and filter the full set. All studies are sourced from PubMed (NCBI/NIH) and enriched with citation counts from OpenAlex.
ACTIVE CLINICAL TRIALS
Sourced from ClinicalTrials.gov (NIH). Pulled at page build time; check the registry for live status.
No active trials returned for the current query. The full registry is searchable at clinicaltrials.gov.
HOW WE BUILT THIS
This page is auto-generated from PubMed (NCBI/NIH), OpenAlex, and ClinicalTrials.gov. We update it weekly. No study is added that hasn't been peer-reviewed. No paid placement, no editorial bias, no “studies we like”. Just the public record.
Sources. Studies are pulled from PubMed (NCBI/NIH) using the query ("molecular hydrogen" OR "hydrogen therapy" OR "H2 therapy" OR "hydrogen-rich water" OR "hydrogen inhalation") AND (oxidative stress OR antioxidant OR inflammation OR recovery OR longevity), filtered to the last 20 years. Citation counts are pulled from OpenAlex. Active trials are pulled from ClinicalTrials.gov v2. Every PMID, DOI, journal, and author list is verified against the original record before publication.
Featured vs. all. The “Featured” section is a hand-curated set of 8 foundational studies (the Ohsawa 2007 Nature Medicine paper and seven others, including a 2023 systematic review of 64 human studies and 81 clinical trials). The “All studies” table is the full PubMed result set for our query — the field is broader than any curation could capture.
Honest mixed results included. A 2024 study by Zhou et al. found that hydrogen-rich water improved objective power output in trained men but did not improve subjective recovery markers. We include it in the featured set on purpose — the transparency promise is to show what the literature actually says, not just the wins.
Update cadence. This page was last regenerated on August 20, 2026. The next scheduled refresh is one week from today. To re-pull the data on demand, run python3 scripts/research-pull.py from the repository root.
Read the 4-article primer — what H₂ is, how it differs from hydrogen water, what the Ohsawa 2007 paper actually found, and what the human safety data looks like.
Read the 4-article primer →